R&DFermentation Technology

Optimization of Probiotic Production with Own Technologies and Expertise

Key Processes

Probiotic Fermentation Optimization Technology That Guarantees Highest Quality

To ensure optimal state of living bacteria, we have optimized the fermentation conditions for each strain and established mass production facilities through continuous technology innovations as a means to secure global-scale fermentation facilities.

01Prefermentation
Process of Preparing Strains for Main Fermentation
02Inoculation
Process of Inoculating Strains into the Fermentation Medium
03Fermentation
Main Fermentation Process of Probiotics
04Bacterial Cell Harvest
Process of Separating Probiotics from the Original Broth by Centrifugation
05Dual Coating
Coating Process of Probiotics with Specially Formulated Coating Materials of Protein and Polysaccharide Using World Patented Technology
06Lyophilization
Process of Removing Moisture from Probiotics
07Milling
Process of Grinding Probiotics into Appropriate Particle Size
08Probiotic Raw Material Products

Probiotic Coating Technology

Cell Biotech has developed Dual Coating technology that maximizes survival rate of probiotics in the intestine as a result of over 20 years of research on probiotics only. As a global technology patented in Korea, USA, EU, Japan and China, Dual Coating technology has spearheaded a new paradigm in coating technologies. Through continuous technological innovations, Cell Biotech possesses advanced coating technologies for probiotics, such as Triple Coating and Multi-Coating, which are being utilized in various industries to create a new added value for probiotic sector.

World-recognized Probiotics coating technology Dual Coating

Probiotic Coating Technology Recognized by the World Dual Coating

- Development of pH-dependent Release System Using Protein & Polysaccharide Unique probiotic coating technology patented across the world, including Korea, USA, EU, Japan and China. Significantly increases chances of probiotics vulnerale to high temperature, moisture, and mechanical pressure surviving through gastric acid and bile salt to reach the intestine. Maximizes stability of probiotics during manufacture, storage and distribution.

no coated
비코팅
Dual Coated
이중코팅
Triple Coating
- Coating technology with additional coating of nanoparticles on probiotics coated with protein and polysaccharide.
- Triple coating technology ensures excellent gastric acid resistance, bile salt resistance and stability of probiotics.
- Possible to develop into various formulations as functional foods, cosmetics, etc., while maintaining the physiologically active functions of probiotics.
Multi-Coating
- Coating technology with oil coating added to probiotics coated with protein, polysaccharide and nanoparticles.
- Multi-coating enhances resistance of probiotics against heat, gastric acid and bile salt.
- In particular, oil coating effectively complements the intrinsic weakness of probiotics against moisture to allow for various formulations during product development.

Fermentation Specialists

Cell Biotech's Core Human Resource Development Program

Fermentation and all core processes of production at Cell Biotech are operated by fermentation specialists. Fermentation specialists are cultivated through Cell Biotech's core human resource development program, which is designed to raise specialists of various sectors in probiotic industry with a wide range of training, including profound knowledge on microorganisms, practical education and training at fermentation sites.

Fermentation Specialist. 01 Research Specialist 02 Development Specialist 03 Quality Management Specialist
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